Biomarker

Metabolomic aging clocks (MileAge and MetaboAgeMort)

Source-reviewedGoverned LongevityNext intelligence profile

Evidence reviewed through2026-08-07

Executive intelligence snapshot

Current reviewed view

Risk stratification research within matched populations and platforms

This profile includes 0 reviewed relationship(s) and 2 reviewed source(s).

This view is bounded by reviewed evidence and does not provide a recommendation or a claim beyond the stated review date.

Evidence state

Source-reviewed

Evidence reviewed through2026-08-07

Evidence state

What the evidence supports

Risk stratification research within matched populations and platforms

Evidence boundary

Key limitations

Intervention response, biological-age reversal, clinical utility or surrogate use
Does not establish efficacy, mechanism falsification, approval, utility, rejuvenation, or investment attractiveness.

Not established

Key unknowns

Clinical utility, treatment-selection utility, surrogate validity, portability, and unreviewed post-freeze evidence remain unknown unless explicitly supported.
The reviewed evidence does not resolve this dimension beyond the recorded boundary.

Next evidence milestone

What would change this view?

Locked external validation in independent populations and prospective intervention testing

Evidence reviewed through 2026-08-07.

Intelligence connections

No reviewed related intelligence is recorded for this profile. No relationship is inferred.

Reviewed source layer

Evidence & sources

These cards show only metadata present in the reviewed source registry.

bibliographic index

A novel metabolomic aging clock predicting health outcomes and its genetic and modifiable factors

PubMed / U.S. National Library of Medicine

Reference: PMID 39331845; bounded citation metadata and abstract review via NCBI E-utilities

Reviewed: 2026-08-06

bibliographic index

MileAge: a metabolomic aging measure in UK Biobank

PubMed / U.S. National Library of Medicine

Reference: PMID 39693428; bounded citation metadata and abstract review via NCBI E-utilities

Reviewed: 2026-08-06

Technical provenance

Object key: biomarker:metabolomic_age
Source release: LNPG-REL-20260807-027
Mapping version: 0.2.0
Presentation release: LNPG-REL-20260808-037
Projection hash: c25409a91cc706a6ba549487267e966eb67e061fc32db01b4d21ec87489a72be

Source identifiers

LNPG-SRC-56dc241d-a38e-4beb-b945-36d2eaf0001e
LNPG-SRC-f7df2407-5256-456d-a885-1884b27654fd

Directed relationship identities

No directed relationship identity is recorded.

Scores are not displayed because no score methodology is qualified for this profile.

Presentation contract

Snapshot mode: DIRECT_GOVERNED_SUMMARY