Intervention

Nicotinamide riboside

Source-reviewedGoverned LongevityNext intelligence profile

Evidence reviewed through2026-08-07

Executive intelligence snapshot

Current reviewed view

Muscle NAD-related metabolites changed, but mitochondrial bioenergetics did not improve.

This profile includes 4 reviewed relationship(s) and 4 reviewed source(s).

This view is bounded by reviewed evidence and does not provide a recommendation or a claim beyond the stated review date.

Evidence state

Source-reviewed

Evidence reviewed through2026-08-07

Evidence state

What the evidence supports

Muscle NAD-related metabolites changed, but mitochondrial bioenergetics did not improve.

Evidence boundary

Key limitations

The study demonstrated oral availability to aged muscle and anti-inflammatory signatures; it did not test long-term clinical function.
Does not establish efficacy, mechanism falsification, approval, utility, rejuvenation, or investment attractiveness.

Not established

Key unknowns

Dose, route, population, and outcomes not recorded in this reviewed profile remain unknown.
The reviewed evidence does not resolve this dimension beyond the recorded boundary.

Next evidence milestone

What would change this view?

No specific evidence milestone is recorded yet.

Evidence reviewed through 2026-08-07.

Intelligence connections

Linked company

Aarhus University Hospital

Company

Linked company

University of Birmingham

Company

Tested in